Liver fibrosis is a term that refers to the degree of liver scarring or damage which CHB can cause. There are a number of ways to assess liver fibrosis, liver biopsy being the gold standard, which broadly categorise fibrosis as mild, moderate or severe. Here we use Fibroscan scores to assess the degree of scar tissue to in your liver.
Fibroscan score <7kPa ~ no or mild fibrosis only
Fibroscan score 7-10kPa ~ moderate fibrosis
Fibroscan score >10kPa ~ severe fibrosis or cirrhosis
Please use your recent clinical test results to answer the following questions:
CHB can cause liver inflammation, which if persistent can result in the development of liver scarring or fibrosis. When significant inflammation is present (or persistent), treatment should be considered.
Liver function tests are used to reflect or interpret the degree of inflammation. Here we use the serum ALT to grade inflammation.
Serum ALT <30 ~ no inflammation
Serum ALT 30-60 ~ mild to moderate inflammation
Serum ALT >60 ~ Significant inflammation
CHB can cause liver inflammation, which if persistent can result in the development of liver scarring or fibrosis. When significant inflammation is present (or persistent), treatment should be considered.
Liver function tests are used to reflect or interpret the degree of inflammation. Here we use the serum ALT to grade inflammation.
Serum ALT <30 ~ no inflammation
Serum ALT 30-60 ~ mild to moderate inflammation
Serum ALT >60 ~ Significant inflammation
CHB can cause liver inflammation, which if persistent can result in the development of liver scarring or fibrosis. When significant inflammation is present (or persistent), treatment should be considered.
Liver function tests are used to reflect or interpret the degree of inflammation. Here we use the serum ALT to grade inflammation.
Serum ALT <30 ~ no inflammation
Serum ALT 30-60 ~ mild to moderate inflammation
Serum ALT >60 ~ Significant inflammation
CHB can cause liver inflammation, which if persistent can result in the development of liver scarring or fibrosis. When significant inflammation is present (or persistent), treatment should be considered.
Liver function tests are used to reflect or interpret the degree of inflammation. Here we use the serum ALT to grade inflammation.
Serum ALT <30 ~ no inflammation
Serum ALT 30-60 ~ mild to moderate inflammation
Serum ALT >60 ~ Significant inflammation
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Viral load (or HBV DNA) reflects the amount of replicating virus in the blood. Measuring HBV DNA quantifies the amount of virus in the bloodstream, which is an important parameter to determine whether treatment is indicated or not.
HBV DNA <2,000IU/ml ~ low viral load
HBV DNA between 2,000IU/ml and 20,000IU/ml ~ moderate viral load
HBV DNA >20,000IU/ml ~ high viral load
Based on the current clinical parameters provided, treatment is indicated. I would recommend you discuss your latest results with your treating physician as a matter of urgency. Please note: All patients with CHB should be under specialist follow-up.